Natural ingredients we’re proud of


(Ben-ZISO-thia-ZO-li-none) Synthetic Other names: BIT

What is Benzisothiazolinone

Benzisothiazolinone, also called BIT, is an off-white to yellowish liquid antimicrobial substance.[1] 

What Benzisothiazolinone does in our products

Benzisothiazolinone is a preservative, but it is also a disinfectant used in the film, fiber, leather, masonry, metalworking, and embalming industries. However, it is also found in liquid hand soap and sunscreen.[2] It dissolves in water and is used in water-based solutions, such as pastes, paints, and oils.[3] 

Which products include Benzisothiazolinone

Natural Baby Dish Soap
Natural Baby Laundry Detergent
Natural Baby Multi-Surface Cleaner
Natural Baby Stain Remover
Natural Carpet & Upholstery Shampoo
Natural Dish Soap
Natural Dish Soap Citrus & Sea Salt
Natural Dish Soap Green Tea & Lime
Natural Dish Soap Organic Lemongrass
Natural Laundry Detergent
Natural Laundry Detergent Free & Clear
Natural Laundry Detergent Fresh Linen
Natural Multi-Surface Cleaner
Natural Multi-Surface Cleaner Green Tea & Lime
Natural Multi-Surface Cleaner Organic Lemongrass
Natural Pet Stain & Odor Remover
Natural Stain Remover

How Benzisothiazolinone made

There are three common methods for making BIT. The first involves reacting 2-halogenothiobenzoyl halide with a primary amine to obtain an N-substituted BIT. The 2-halogenothiobenzoyl halide is typically made by cleaving the disulphide bond of 2,2'-dithio-bis-benzoic acid with halogen and simultaneously or sequentially converting the carboxylic acid groups to acid halides. A second method involves cyclising 2-halogenothiobenzamide in the presence of acid or alkali. The 2-halogenothiobenzamide typically comes from converting 2,2'-dithio-bis- benzoic acid to bisamide and then cleaving the disulphide bond with halogen. The third method is to heat 2,2'-dithio-bis-benzamides in the presence of a sodium hydroxide solution. Another method is to disproportion bisamide in alkali in the presence of oxygen or an oxygen-release agent.[4] 

Why we use Benzisothiazolinone

We use benzisothiazolinone in several of our products as a biodegradable preservative that is a better alternative to formaldehyde, methylisothiazolinone, and medium-chain triglycerides. The Scientific Committee on Consumer Safety considers the ingredient safe when used as a preservative up to 0.01% in cosmetics. Whole Foods has deemed the ingredient acceptable in its body care and cleaning product quality standards.[5,6,7] In addition, research shows the ingredient is not a strong skin irritant in skin cream up to 100ppm.[8]